The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on top-rated NFL picks since its inception. 49ers picks, be sure to check out the NFL predictions and betting advice from the SportsLine Projection Model. Cowboys odds from Caesars Sportsbook, while the over/under for total points scored is 47. San Francisco is a four-point favorite in the latest 49ers vs. Kickoff from Levi's Stadium in Santa Clare, California, is set for 6:30 p.m. On Sunday in the 2023 NFL playoff bracket, San Francisco (14-4) will square off against the Cowboys (13-5), who have lost six straight Divisional Round games, the longest such streak by any team since 1970. They have not lost in the round since falling to Tampa Bay in January 2003. The 49ers have won five straight games in the Divisional Round, a streak that dates back to January 2012. The San Francisco 49ers will try to win their sixth straight Divisional Round playoff game when they host the Dallas Cowboys in the 2023 NFL playoffs on Sunday.